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Last Updated: 21 March 2026Verified for JEE 2026
BiologyNEET

Difference Between Prokaryotic Cell and Eukaryotic Cell

Prokaryotic and eukaryotic cells are the two fundamental cell types. Prokaryotes lack a membrane-bound nucleus, while eukaryotes have a well-defined nucleus and organelles.

Prokaryotic Cell vs Eukaryotic Cell — Comparison Table

AspectProkaryotic CellEukaryotic Cell
NucleusNo true nucleus (nucleoid)Membrane-bound nucleus
SizeSmall (1-10 μm)Large (10-100 μm)
OrganellesNo membrane-bound organellesMitochondria, ER, Golgi, etc.
DNACircular, no histonesLinear, with histones
Ribosomes70S80S
Cell wallPresent (peptidoglycan)Present in plants (cellulose), absent in animals
ReproductionBinary fissionMitosis and meiosis
ExamplesBacteria, ArchaeaPlants, Animals, Fungi, Protists

Key Points to Remember

Prokaryotes evolved first (~3.5 billion years ago)
Endosymbiotic theory: mitochondria and chloroplasts were once prokaryotes
Prokaryotes can have plasmids (extra-chromosomal DNA)
Both types have plasma membranes, ribosomes, and DNA

Exam Relevance

This topic falls under Cell Structure in Biology for NEET. Questions on the difference between prokaryotic cell and eukaryotic cell appear frequently in competitive exams, both as direct MCQs and as part of numerical/assertion-reason problems.

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