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Last Updated: 22 March 2026Verified for JEE 2026
BiologyNEET

Difference Between DNA and RNA

DNA and RNA are the two types of nucleic acids essential for life. DNA stores genetic information, while RNA helps in protein synthesis.

DNA vs RNA — Comparison Table

AspectDNARNA
Full formDeoxyribonucleic AcidRibonucleic Acid
SugarDeoxyriboseRibose
BasesA, T, G, CA, U, G, C
StructureDouble-stranded helixUsually single-stranded
LocationNucleus (mainly)Nucleus and cytoplasm
FunctionStores genetic informationProtein synthesis, gene regulation
StabilityMore stableLess stable
TypesOnly one typemRNA, tRNA, rRNA, snRNA

Key Points to Remember

DNA replication is semi-conservative (Meselson-Stahl experiment)
Central Dogma: DNA → RNA (transcription) → Protein (translation)
RNA can act as enzyme (ribozymes)
DNA has thymine; RNA has uracil instead

Exam Relevance

This topic falls under Molecular Basis of Inheritance in Biology for NEET. Questions on the difference between dna and rna appear frequently in competitive exams, both as direct MCQs and as part of numerical/assertion-reason problems.

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